Ataxia-telangiectasia (AT) is a rare disease that causes a variety of neurological deficits. Patients with AT lose their ability to move their eyes and limbs in response to commands. They become stiff and weak. In some cases, their mental faculties deteriorate as well. This is why it is called a ‘neuron degenerative’ disorder. The cells of the nervous system have a cell surface membrane called the ‘cell membrane’.
| banks in dubai |
| fab bank balance check |
| instant cash loan in 1 hour dubai |
The membrane keeps the cells apart from each other. When a virus invades the cell, it must enter the cell’s cytoplasm. If the virus enters the cell through the cell membrane, it can infect the cell. The membrane can only allow small substances to pass through it.
This means that larger substances cannot pass through Blocking Antibody the membrane. In order to get larger substances through the membrane, viruses use proteins called’receptors’ to bind to the membrane. The receptor molecules are made up of two parts. One part attaches to the membrane of the cell, and the other part interacts with the virus to enable the virus to attach to the cell.
The disease is caused by mutations of the gene ATXN 2, which encodes the protein Ataxin 2. The mutation causes Ataxin 2 to accumulate in the nuclei of the cells.
